进口Data

进口, visualize, and preprocess experimental data, including Excel, CSV, SAS XPORT, and NONMEM

进口tabular data from files to estimate model parameters. Supported file types include Excel^®, text, SAS^®XPORT, and NONMEM^®-formatted files. Visualize and categorize the data in theSimBiology Model Analyzerapp or at the command line. Use the time course data of measured drug concentrations to perform noncompartmental analysis (NCA) and calculate PK parameters.

Apps

SimBiology Model Builder	Build QSP, PK/PD, and mechanistic systems biology models interactively
SimBiology Model Analyzer	Analyze QSP, PK/PD, and mechanistic systems biology models

Functions

`groupedData2table`	Convert groupedData object to table
`sbionca`	Compute noncompartmental analysis (NCA) parameters (requiresStatistics and Machine Learning Toolbox)
`sbioncaoptions`	Specify options to calculate noncompartmental analysis (NCA) parameters
`sbionmimport`	进口NONMEM-formatted data
`sbionmfiledef`	NONMEMfile definition object for sbionmimport
`sbiotrellis`	Plot data or simulation results in trellis plot
`sbioplot`	Plot simulation results in one figure
`sbiosubplot`	Plot simulation results in subplots

Objects

`groupedData`	Table-like collection of data and metadata
`SimData`	Simulation data

Examples and How To

App Workflow

Calculate NCA Parameters and Fit Model to PK/PD Data Using SimBiology Model Analyzer App
Perform noncompartmental analysis and calibrate model parameters by fitting to experimental PKPD data using nonlinear regression.

Programmatic Workflow

进口ing Data
SimBiology lets you import tabular data from external sources programmatically.

Concepts

进口ing Data — Supported Files and Data Types
SimBiology lets you import external data saved in several file formats, such as Excel files, text files, and NONMEM-formatted files.
Noncompartmental Analysis
NCA (noncompartmental analysis) lets you calculate pharmacokinetic parameters of a drug without requiring the assumption of a compartmental model.